When e-mail arrives in my inbox I do one of two things, if it requires a reply in under twenty-four hours I typically flag it for follow up and leave it in the Inbox (just to annoy me). If it requires a follow up outside of that time frame I typically "move" the item to my Tasks folder which results in the e-mail being embedded into a Task.
This works well because the Task will typically pop up some time in the middle of the night and give me a nice TODO list for the following day. Quite often those tasks are no longer relevant because the issues have resolved themselves (strange how this happens), or they are such low priority that it becomes a best effort and I put it off until a later date.
This means that higher priority items (of which there are always some) dominate my day. Unfortunately my internal threading model is not flawless because sometimes low priority items become high priority items and I don't notice.
That is what happened when I filed a message from my blog about some comment spam that someone had posted up. I put it off and now my blog is at best temporarily associated with some of the seedier parts of the Internet. Well, I just cranked up the priority of these particular tasks to ensure they are cleared up in the next twenty-four hours.
Hopefully this won't go on my "permanent google record".